Fig. 4: Quantitative acetylome of rat islets in response to glucose. | Cell Death & Disease

Fig. 4: Quantitative acetylome of rat islets in response to glucose.

From: The pivotal role of protein acetylation in linking glucose and fatty acid metabolism to β-cell function

Fig. 4

a Proteomic workflow for the quantification of Kac sites and proteins in rat islets in response to low and high glucose. b GO-based enrichment analysis of glucose-regulated hyperacetylated proteins. c Subcellular distribution of glucose-regulated hyperacetylated proteins. d KEGG pathway-based enrichment analysis of glucose-regulated hyperacetylated proteins. e Mitochondrial fatty acid β-oxidation and TCA cycle enzymes (gene symbols) are highlighted next to the reaction they catalyze, with hyperacetylated enzymes targeted by high glucose colored in yellow. Logarithmized corrected p-values for significant overrepresentation are shown

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