Fig. 5: AGAP2-AS1 facilitates PC cell migration and invasion in vitro. | Cell Death & Disease

Fig. 5: AGAP2-AS1 facilitates PC cell migration and invasion in vitro.

From: RREB1-induced upregulation of the lncRNA AGAP2-AS1 regulates the proliferation and migration of pancreatic cancer partly through suppressing ANKRD1 and ANGPTL4

Fig. 5

MTT assays were performed to detect the proliferation of AsPc-1 and BxPC-3 cells treated with empty vector, pcDNA-RREB1, pcDNA-RREB1 + si-NC, or pcDNA-RREB1 + si-AGAP2-AS1, and of PANC-1 cells treated with si-NC, si-RREB1, si-RREB1 + empty vector, or si-RREB1 + pcDNA-AGAP2-AS1. b, c Transwell assays were performed with si-AGAP2-AS1-transfected AsPC-1 cells to determine the effects of AGAP2-AS1 on cell migration and invasion. d, e Transwell assays were performed with si-AGAP2-AS1-transfected BxPC-3 cells to determine the effects of AGAP2-AS1 on cell migration and invasion. f, g Transwell assays were performed with pcDNA-AGAP2-treated PANC-1 cells to determine the effects of AGAP2-AS1 on cell migration and invasion. The cells on the underside of the membrane were stained and counted. *P < 0.05, **P < 0.01, ***P < 0.001

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