Fig. 6: AGAP2-AS1 promotes the tumorigenesis of PC cells in vivo. | Cell Death & Disease

Fig. 6: AGAP2-AS1 promotes the tumorigenesis of PC cells in vivo.

From: RREB1-induced upregulation of the lncRNA AGAP2-AS1 regulates the proliferation and migration of pancreatic cancer partly through suppressing ANKRD1 and ANGPTL4

Fig. 6

Tumor volumes were measured and recorded every 2 days after injection. The mean tumor volume is represented by dots and the bars represent SD (n = 5). b BxPC-3 cells transfected with empty vectors and sh-AGAP2-AS1 were injected into nude mice (n = 5) with the same concentration and amount. c Tumors were removed and weighed and recorded on day 16 postinjection; their weights are expressed as mean tumor weight ± SD. d The expression levels of AGAP2-AS1 in xenograft tumors were detected by qRT-PCR (n = 5). e, f Tumor sections were examined using H&E and IHC staining with antibodies against Ki-67. Error bars represent mean ± standard error. *P < 0.05, **P < 0.01, ***P < 0.001

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