Fig. 7: Immunohistological (IHC) staining of ADAM19 and SCNN1A in non-small cell lung cancer is associated with epithelial–mesenchymal transition (EMT) status.
From: EMT is associated with an epigenetic signature of ECM remodeling genes
a Representative staining of IHC against VIMENTIN, ADAM19, and SCNN1A showing a positive correlation between ADAM19 and VIMENTIN expression levels and an inverse correlation between VIM and SCNN1A in 30 patients tumors classified as EMT-positive. b Top: quantifications of ADAM19 and SCNN1A staining in regard to EMT status (percentage of patients). Bottom: mean of IHC score in VIM+ and VIM tumors
