Fig. 4: Sphingosine-1-phosphate receptor 1 (S1PR1) suppressed VE-cadherin expression and promoted β-catenin expression. | Cell Death & Disease

Fig. 4: Sphingosine-1-phosphate receptor 1 (S1PR1) suppressed VE-cadherin expression and promoted β-catenin expression.

From: S1PR1 regulates the switch of two angiogenic modes by VE-cadherin phosphorylation in breast cancer

Fig. 4

a Western blots showed that downregulation of S1PR1 increased the expression levels of VE-cadherin and weakened β-catenin expression. b Immunofluorescence staining. S1PR1 may induce a positional change in β-catenin in breast cancer cells and decrease VE-cadherin expression (bar, 50 µm). The mean ± SD is shown. *p < 0.05 (n = 3)

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