Fig. 2: Neuronal proteins exhibiting significant temporal changes in abundance in response to glutamate overstimulation. | Cell Death & Disease

Fig. 2: Neuronal proteins exhibiting significant temporal changes in abundance in response to glutamate overstimulation.

From: Quantitative proteomic analyses of dynamic signalling events in cortical neurons undergoing excitotoxic cell death

Fig. 2

a Volcano plots depicting the distribution of quantified neuronal proteins identified at 5, 15, 30, 60 and 240 min of glutamate treatment. Selected neuronal proteins showing significant changes (±2.5-fold changes, p ≤ 0.05) in abundance are also highlighted b Heatmap depicting the time-dependent changes in abundance of selected neuronal proteins in response to glutamate treatment. Only proteins exhibiting ± 2.5-fold differences in abundance in at least one of the five time points are selected for presentation. The temporal changes (abundance ratios) of all identified proteins are presented in Table S1. White boxes indicate that the abundance ratio information is missing for those given proteins in any of the replicate samples

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