Fig. 6: Luteolin reduced cell proliferation and causes G2/M phase arrest in A549 and H460 cells. | Cell Death & Disease

Fig. 6: Luteolin reduced cell proliferation and causes G2/M phase arrest in A549 and H460 cells.

From: Decrease of AIM2 mediated by luteolin contributes to non-small cell lung cancer treatment

Fig. 6

Cells were pretreated with siAIM2 or AIM2 overexpression plasmid before treating with or without luteolin (40 μM) for 24 h. a MTT method for cell proliferation analysis. b Representative flow histograms depicted cell cycle distribution and summarized flow cytometry data. c Western blot for the expressions of cyclin B1, p-cdc2 (Tyr15), cdc2 and p21. *P < 0.05, **P < 0.01, ***P < 0.001 vs control, #P < 0.05, ##P < 0.01, ###P < 0.001 vs luteolin (40 μM). NS no significant difference

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