Fig. 1: Gpr174 KO mice were resistant to LPS-induced endotoxemia and CLP -induced sepsis. | Cell Death & Disease

Fig. 1: Gpr174 KO mice were resistant to LPS-induced endotoxemia and CLP -induced sepsis.

From: Gpr174-deficient regulatory T cells decrease cytokine storm in septic mice

Fig. 1

a WT and Gpr174 KO (n = 20 mice/group) mice were injected (intraperitoneal injection, i.p.) with LPS (10 mg/kg). Survival rate was monitored for 48 h. b WT and Gpr174 KO (n = 20 mice/group) mice were subjected to CLP. Survival rate was monitored for 168 h. Mortality rates were compared using Kaplan–Meir method with Log-rank Test. *P < 0.05

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