Fig. 6: Gpr174-deficient Treg cells were associated with a dominance of M2-like macrophages in LPS-induced sepsis.
From: Gpr174-deficient regulatory T cells decrease cytokine storm in septic mice
Methods as described in Fig. 5. a A representative flow cytometry result of M2-like (F4/80highCD14high) macrophages were defined within total peritoneal macrophages following co-staining with F4/80 and CD11b. b–c Quantification of M2-like macrophages extracted from PBS or LPS challenged mice. d Quantification of M2-like macrophages extracted from LPS challenged mice after PC61 injection. e Quantification of M2-like macrophages extracted from LPS challenged mice after adoptive transfer. Data are representative of three independent experiments (n = 3 mice/group). Data are shown as mean ± S.D. *P < 0.05
