Fig. 5: GSK’074 does not induce apoptosis. | Cell Death & Disease

Fig. 5: GSK’074 does not induce apoptosis.

From: Identification of a novel class of RIP1/RIP3 dual inhibitors that impede cell death and inflammation in mouse abdominal aortic aneurysm models

Fig. 5

a, b, d, e L929 cells were treated with indicated compounds for 24 h, then stained with Annexin V-PE and 7-AAD and analyzed by flow cytometry. Apoptotic cells were identified as PE Annexin V+/7-AAD−. c L929 cells were treated with 10 μM GSK’843 or GSK’074 for 24 h, cell lysates were immunoprecipitated with anti-RIP1 antibody followed by immunoblot analysis with the indicated antibodies. *P < 0.05

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