Fig. 2: Set knockout mice are embryonic lethal.
From: Loss of SET reveals both the p53-dependent and the p53-independent functions in vivo
a Pictures of the representative embryos from the intercross between set+/− mice are shown, 1–5: set+/+ embryos, and 6–10: set−/− embryos. 1 and 6: embryonic day 8.5 (E8.5); 2 and 7: E9.5; 3 and 8: E10.5; 4 and 9, E11.5; 5 and 10: E12.5. b Comparison of the size of the embryos during embryonic development. c E10.5 set+/− (2) is comparable to the E10.5 set+/+ (1) embryo. Abnormalities in the E10.5 set−/− embryo include cardiac edema (3: arrow), open neural tube (3: *), and slowed growth (4)
