Fig. 5: p27 and p18 are dispensable for genomic stability at iPSC stage. | Cell Death & Disease

Fig. 5: p27 and p18 are dispensable for genomic stability at iPSC stage.

From: Absence of cyclin-dependent kinase inhibitor p27 or p18 increases efficiency of iPSC generation without induction of iPSC genomic instability

Fig. 5

a Representative images of spindle abnormal phenotype. Bars: 1.5 μm. b Abnormal centrosomes in various iPSCs at the indicated time points post 2-Gy IR. c Tail intensity of the cells in various iPSCs at the indicated time points post 2-Gy IR. d Western blot assays of expression of cleaved PARP in various iPSCs at the indicated time points post 2-Gy IR. e FACS analysis of apoptosis at the indicated time points post 2-Gy IR. Data are representative of two or three independent experiments. Error bars, ±SD. **p < 0.01, ***p < 0.001, by two-tailed t test

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