Fig. 5: Inhibition of HIF-1α attenuates OS cell invasion and angiogenesis. | Cell Death & Disease

Fig. 5: Inhibition of HIF-1α attenuates OS cell invasion and angiogenesis.

From: Long non-coding RNA Taurine upregulated gene 1 promotes osteosarcoma cell metastasis by mediating HIF-1α via miR-143-5p

Fig. 5

a HIF-1α expression levels in OS cells (143B and U2OS) transfected with HIF-1α siRNAs (si HIF-1α) were detected by qRT-PCR and western blots. b, c HIF-1α knockdown inhibited OS cell migration (Scale bar = 50 μm), HUVECs angiogenesis (Scale bar = 100 μm), and proliferation. d HIF-1α knockdown inhibited OS cell proliferation. **P < 0.01; ***P < 0.001

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