Fig. 2: NMN expanded MSCs have enhanced osteogenesis but reduced adipogenesis capacity in an in vitro culture system. | Cell Death & Disease

Fig. 2: NMN expanded MSCs have enhanced osteogenesis but reduced adipogenesis capacity in an in vitro culture system.

From: Nicotinamide mononucleotide promotes osteogenesis and reduces adipogenesis by regulating mesenchymal stromal cells via the SIRT1 pathway in aged bone marrow

Fig. 2

a Scheme of NMN administration and osteogenesis and adipogenesis. b, c Representative images showing osteogenesis (b) and adipogenesis (c). d, e The percentages of fibroblast colonies that contained osteogenetic (d) and adipogenetic (e) differentiation of CFU-F. f–i qPCR analysis of transcript levels for regulators of osteogenic (f, g) and adipogenic (h, i) differentiation are shown (n = 3 independent experiments). *p < 0.05, **p < 0.01 error bars, s.d.

Back to article page