Fig. 7: Signaling pathway altered by PRMT1 overexpression in ESCC cells. | Cell Death & Disease

Fig. 7: Signaling pathway altered by PRMT1 overexpression in ESCC cells.

From: PRMT1 regulates the tumour-initiating properties of esophageal squamous cell carcinoma through histone H4 arginine methylation coupled with transcriptional activation

Fig. 7

a Four differentially expressed transcripts were validated by qRT-PCR in PRMT1 overexpression ECA109 and TE1 cells. Data is shown as the mean ± SD, *P < 0.05, **P < 0.01. b, c qRT-PCR analysis for the selected Wnt and Notch target genes in ECA109 and TE1 cells. Data is shown as the mean ± SD, *P < 0.05, **P < 0.01. d, e Western blot of active (Non-phospho) β-catenin and Notch1 in ECA109 and TE1 with PRMT1 overexpression

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