Fig. 1: Perifosine enhances the killing of TNBC cells by Olaparib. | Cell Death & Disease

Fig. 1: Perifosine enhances the killing of TNBC cells by Olaparib.

From: A novel UCHL3 inhibitor, perifosine, enhances PARP inhibitor cytotoxicity through inhibition of homologous recombination-mediated DNA double strand break repair

Fig. 1

a, b Colony formation assay of MDA-MB-231 (a) or BT-549 (b) cells after treatment with 3 µM Olaparib, 50 nM, or 10 μM perifosine or their combination. c Western blot analysis of Akt, p-Akt, FOXO1, p-FOXO1, GSK-3β, and p-GSK-3β after 50 nM or 10 μM perifosine treatment for 24 h. β-actin was used as a loading control. **P < 0.01, ***P < 0.001, and n.s. no significance

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