Fig. 1: Pterostilbene (PT) inhibits the proliferation of hepatocellular carcinoma (HCC) cells. | Cell Death & Disease

Fig. 1: Pterostilbene (PT) inhibits the proliferation of hepatocellular carcinoma (HCC) cells.

From: Inhibition of eIF2α dephosphorylation accelerates pterostilbene-induced cell death in human hepatocellular carcinoma cells in an ER stress and autophagy-dependent manner

Fig. 1

a Structure of PT. b Human HCC cell lines (Huh-7, SK-Hep-1, PLC/PRF/5, HA22T/VGH and HepG2) were treated with various concentrations of PT (0, 25, 50, 75 or 100 μM) for 24 h, followed by 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyl-tetrazolium bromide (MTT) assay. c Cell viability was determined through a trypan blue exclusion assay. d Colony formation assay was performed on HCC cells treated with PT for 7 days. e PT-treated cells were harvested and subjected to Annexin V and dead cell flow cytometry assay for the quantitative analysis of apoptosis. *p < 0.05, **p < 0.01 compared with controls. Data are presented as mean ± standard error for three experiments

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