Fig. 1: CTTN interacts with HBx in HepG2 HCC cells. | Cell Death & Disease

Fig. 1: CTTN interacts with HBx in HepG2 HCC cells.

From: The HBx–CTTN interaction promotes cell proliferation and migration of hepatocellular carcinoma via CREB1

Fig. 1

a Analysis of HBx-associated proteins by CoIP-MS in HepG2 cells overexpressing HBx (HBx-HepG2). b Representative MS/MS spectrum of CTTN; the amino acid sequence of a doubly charged peptide with m/z 937.9402 was identified as NASTFEDVTQVSSAYQK from mass differences in the y and b fragment ions series. c Protein sequence of CTTN: the matched peptides are labeled in red bold letters. d CoIP to validate the HBx-CTTN interaction. CTTN was immunoprecipitated by an anti-HBx but not by IgG control. e Expression of HBx and CTTN in the cytoplasm HBx-HepG2 by confocal microscopy

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