Table 1 Correlation between ZNF479 expression and clinicopathologic characteristics of HCC patients

Characters	N	LogT_mRNA–logN_mRNA	p-value
Total	150	0.27 ± 0.83
Age
≤60 y/o	68	0.31 ± 0.87	NS
>60 y/o	82	0.24 ± 0.80	NS
Gender
Male	102	0.32 ± 0.87	NS
Female	48	0.16 ± 0.74	NS
Smoking
Yes	72	0.28 ± 0.85	NS
No	75	0.29 ± 0.81
Unknown	3
Drinking
Yes	31	0.61 ± 0.85	0.013
No	116	0.20 ± 0.80
Unknown	3
Tumor size (diameter)
≤5cm	70	0.43 ± 0.81	0.032
>5cm	80	0.14 ± 0.83	0.032
Pathology type
Solitary	103	0.29 ± 0.82	NS
Multiple	46	0.26 ± 0.84
Infiltrative	1	−1.24
Vascular invasion
Absent	49	0.63 ± 0.80	0.001
Capsular vein invasion	18	0.25 ± 0.84
Portal vein invasion	83	0.07 ± 0.78
AJCC staging
Stage I	41	0.63 ± 0.79	0.007
Stage II	57	0.21 ± 0.79
Stage III	47	0.08 ± 0.87
Stage IV	5	−0.11 ± 0.45
BCLC staging
Stage A	59	0.54 ± 0.80	0.002
Stage B	58	0.20 ± 0.86
Stage C	33	−0.07 ± 0.83
Cirrhosis
Yes	46	0.55 ± 0.94	0.006
No	104	0.75 ± 0.74	0.006
Alpha-fetoprotein
≤80 ng/ml	92	0.30 ± 0.78	NS
>80 ng/ml	58	0.22 ± 0.91	NS
Viral infection
Hepatitis B	50	0.46 ± 0.98	NS
Hepatitis C	50	0.14 ± 0.68
No hepatitis B or C	50	0.22 ± 0.79
Metastasis
Yes	9	−0.05 ± 0.39	NS
No	141	0.29 ± 0.85

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