Fig. 5: PI3K-AKT signaling is indispensable for the anti-tumor function of TC2N.
From: Identification of TC2N as a novel promising suppressor of PI3K-AKT signaling in breast cancer
a The protein level of TC2N, AKT and phosphorylated AKT were analyzed by WB after treatment with AKT inhibitor in stable transfected BC cells. The cell viability was measured by MTS assays after treatment with AKT inhibitor in stable transfected BC cells. c The cell proliferation was measured by MTS assays after treatment with AKT inhibitor in stable transfected BC cells. d A schematic illustration of how TC2N suppresses tumor progression in BC. *P < 0.05; **P < 0.01
