Fig. 3: Overexpression of microRNA-708 (miR-708) decreased glioma cell invasion through reversing the epithelial-to-mesenchymal transition (EMT) phenotype. | Cell Death & Disease

Fig. 3: Overexpression of microRNA-708 (miR-708) decreased glioma cell invasion through reversing the epithelial-to-mesenchymal transition (EMT) phenotype.

From: Silencing of microRNA-708 promotes cell growth and epithelial-to-mesenchymal transition by activating the SPHK2/AKT/β-catenin pathway in glioma

Fig. 3

a The Boyden assay revealed that glioma cell invasion ability was decreased in the LV-miR-708 group. b The in vivo assay revealed that miR-708 decreased the number and size of metastatic pulmonary nodules. c The formation of stress fiber in glioma cells was decreased in the LV-miR-708 group. d The epithelial marker E-cadherin was increased, whereas expression of the mesenchymal markers N-cadherin and vimentin were decreased in the LV-miR-708 group, as determined by western blot assay

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