Fig. 2: Screening and identification of SLC35B4 as a novel downstream gene regulated by YAP1 in gastric cancer cells.

a Heat map of differentially expressed genes between control (infection with lentvirus expressing scramble shRNA) and YAP1-knockdown (infection with lentvirus expressing shYAP1-2) cells. b Comparative intersection analysis of downregulated genes in YAP1-knockdown SGC-7901 and MKN-28 cells. c Seventeen candidated genes were validated in YAP1-knockdown SGC-7901 and MKN-28 cells by qRT-PCR. This experiment was performed three times. d Protein level of YAP1 and mRNA level of SLC35B4 in SGC-7901 and MKN-28 cells with transfection of YAP1 siRNAs. This experiment was performed three times