Fig. 2: Evaluation of apoptotic and necrotic cells in the liver by immunohistochemistry for CC3 and in vivo necrosis assay. | Cell Death & Disease

Fig. 2: Evaluation of apoptotic and necrotic cells in the liver by immunohistochemistry for CC3 and in vivo necrosis assay.

From: Hepatic ferroptosis plays an important role as the trigger for initiating inflammation in nonalcoholic steatohepatitis

Fig. 2

a Measurement of serum liver injury markers after 24 h of control (vehicle) and CCl4 treatment (n = 4; *P < 0.05). b HE staining of sections from control and CCl4-treated livers. c Fluorescence images of PI- and CC3-stained cells in control and CCl4-treated livers. d Fluorescence images of PI- and CC3-stained cells in the liver after 2 days of normal diet or the CDE diet feeding. Scale bar = 100 µm. PI propidium iodide, CCl4 carbon tetrachloride, CC3 cleaved caspase-3

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