Fig. 1: TLR9 expression was increased in mice post-MI hearts and human DCM hearts. | Cell Death & Disease

Fig. 1: TLR9 expression was increased in mice post-MI hearts and human DCM hearts.

From: TLR9 is essential for HMGB1-mediated post-myocardial infarction tissue repair through affecting apoptosis, cardiac healing, and angiogenesis

Fig. 1

a, b Protein expression level of TLR9 in the post-MI14d hearts as detected by western blot (n = 4). c Immunofluorescence and WGA staining analysis of TLR9 expression at the peri-infarct area in mice post-MI14d hearts (bar = 50 μm). d, e Protein expression level of TLR9 in the human hearts (n = 4). f Immunofluorescence and WGA staining analysis of TLR9 expression in human DCM hearts (bar = 50 μm). g Representative immunohistochemical analyses of TLR9 in sham-operated WT and TLR9KO mice and post-MI WT mice, including non-infarct area (NIA), border area (BA), and infarct area (IA) at day 14 post-MI (bar = 50 μm). TLR9 expression was quantified and compared (n = 6). TLR9 protein expression was normalized against GAPDH level (a and d). NS indicates not significant; *P < 0.05 vs. matched control

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