Fig. 3: TLR9 deficiency was detrimental to scar formation and wound healing post-MI. | Cell Death & Disease

Fig. 3: TLR9 deficiency was detrimental to scar formation and wound healing post-MI.

From: TLR9 is essential for HMGB1-mediated post-myocardial infarction tissue repair through affecting apoptosis, cardiac healing, and angiogenesis

Fig. 3

a–c Immunofluorescence analyses of α-SMA (a, bar = 50 μm) and collagen I (b, bar = 50 μm) in the heart tissue at day 7 post-MI (n = 6). d, e α-SMA and smad3 protein expression at day 7 post-MI in the infarct area isolated from WT and TLR9 mice (n = 6). f Gene expression of collagen I (Col I) and collagen III (Col III) at day 14 after MI (n = 6). NS indicates not significant; *P < 0.05 vs. WT sham group; §P < 0.05 vs. WT MI group

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