Fig. 3: Gene expression is altered in Mfn1−/− oocytes.
From: Mitofusin 1 is required for female fertility and to maintain ovarian follicular reserve
a Heatmap illustration showing differentially expressed genes in Mfn1−/− and WT secondary follicle-enclosed oocytes from 8-week-old mice. The color spectrum ranging from red to blue indicates normalized levels of gene expression from high to low. b Volcano plots for RNA-seq comparing Mfn1−/− and WT oocytes. Red spot represents –log10 (p-value) ≥2; blue spot represents the –log10 (p-value) <2. c Pathway enrichment analysis in Mfn1−/− oocytes compared to WT. d, e Heatmap illustration showing differentially expressed genes involved in death receptor signaling and adherens junction signaling in Mfn1−/− oocytes compared to WT. The color spectrum ranging from red to blue indicates normalized levels of gene expression from high to low
