Fig. 3: Gene set enrichment analysis resulted in an enrichment of PI3K/AKT signaling in PTEN-expressing and c-Jun-expressing melanoma cells. | Cell Death & Disease

Fig. 3: Gene set enrichment analysis resulted in an enrichment of PI3K/AKT signaling in PTEN-expressing and c-Jun-expressing melanoma cells.

From: C-Jun drives melanoma progression in PTEN wild type melanoma cells

Fig. 3

a Differential expression analysis via DESeq2 (R, Bioconductor). Heat maps illustrate RNA-Seq differential expression in PTENWT, PTENHemDel, or PTENHomDel cells compared to NHEMs. b RNA-Seq differential expression results combined with c-Jun ChIP-Seq peaks illustrated as heat maps of differentially expressed genes regulated by c-Jun in PTENWT and PTENHemDel cells

Back to article page