Fig. 1: HS intake inhibits SIRT3 expression in BAT. | Cell Death & Disease

Fig. 1: HS intake inhibits SIRT3 expression in BAT.

From: Sirtuin 3-mediated pyruvate dehydrogenase activity determines brown adipocytes phenotype under high-salt conditions

Fig. 1

Adipose tissue was harvested from two WAT depots and interscapular BAT of C57BL/6 mice. a Western blot analysis of SIRT3 expression in BAT and WAT. b Semi-quantitative analysis of SIRT3 level in BAT and WAT. c Western blot images of SIRT3 level in BAT and WAT of C57BL/6 mice with or without HS intake. d SIRT3 level was normalised to that of actin and is presented as fold increase relative to BAT NS and SAT NS group, respectively. e Tissue sections were harvested from BAT of the C57BL/6 mice and labelled with antibody against SIRT3 (green); nuclei were stained with 4′,6-diamidino-2-phenylindole (DAPI; blue). (n = 3/group). Scale bar: 50 μm. Data are presented as mean ± SEM (n = 10/group). **p < 0.01 vs. relative control

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