Fig. 3: LINC00511 impacts ER-negative breast cancer cell proliferation and apoptosis in vitro. | Cell Death & Disease

Fig. 3: LINC00511 impacts ER-negative breast cancer cell proliferation and apoptosis in vitro.

From: The transcriptional landscape of lncRNAs reveals the oncogenic function of LINC00511 in ER-negative breast cancer

Fig. 3

a Cancer gene signature analyses and clustering of GSVA scores for LINC00511 in breast cancer patients obtained from the TCGA database. b CCK-8 analysis of the viability and proliferation of UACC-812 and MDA-MB-231 cells following the knockdown of LINC00511 expression. c CCK-8 analysis of the viability and proliferation of MDA-MB-231 cells following the overexpression of LINC00511 expression. d EdU analysis of the proliferation ability of UACC-812 and MDA-MB-231 cells following the knockdown of LINC00511 expression. e EdU analysis of the proliferation ability of MDA-MB-231 cells following the overexpression of LINC00511 expression. f Analysis of the cell colony formation ability of UACC-812 and MDA-MB-231 cells following the knockdown of LINC00511 expression. The number of colonies was counted on the 14th day after seeding. g Analysis of the cell colony formation ability of MDA-MB-231 cells following the overexpression of LINC00511 expression. The number of colonies was counted on the 14th day after seeding. h Flow cytometry (cell apoptosis) analysis of the apoptosis of UACC-812 and MDA-MB-231 cells following the knockdown of LINC0051 expression. Data are shown as the mean ± SD. Student’s t test was used for the statistical analysis: *p < 0.05; **p < 0.01; ***p < 0.001. Data represent three independent experiments

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