Fig. 7 | Cell Death & Disease

Fig. 7

From: The Hippo effector TAZ promotes cancer stemness by transcriptional activation of SOX2 in head neck squamous cell carcinoma

Fig. 7

TAZ and SOX2-correlated gene signature predicts survival of patients with HNSCC. a A total number of 1312 overlapped genes were identified from TAZ-correlated and SOX2-correlated genes download in cBioPortal TCGA-HNSCC dataset. b These overlapped genes were significantly enriched in multiple CSCs-related pathways as assessed by KEGG analyses. c These overlapped genes were significantly enriched in CSCs-related pathways as assessed by GO analyses. d Detailed information regarding 5 candidate genes which were incorporated into a prognostic risk score. e The optimal cutoff value for the prognostic score was generated by ROC curve using TCGA-HNSCC as training cohort. f Kaplan–Meier plot indicated that patients with high scores had much inferior survival as compared to those with low scores (Log-rank test)

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