Fig. 2: Effects of SEPT9_i1 on cell morphology, motility and migration in MCF-7 cell lines. | Cell Death & Disease

Fig. 2: Effects of SEPT9_i1 on cell morphology, motility and migration in MCF-7 cell lines.

From: SEPT9_i1 regulates human breast cancer cell motility through cytoskeletal and RhoA/FAK signaling pathway regulation

Fig. 2

a Western blot for SEPT9_i1 in control, two SEPT9-Knockdown MCF-7 cell lines and two SEPT9-Overexpression cell lines (***p < 0.001). b Phase-contrast microscope images of control, SEPT9-knockdown and SEPT9-Overexpression cells with altered cell morphology (×200). c The motility of cells was measured by a wound healing assay (×40) (*P < 0.05, compared with control group). d Transwell migration assays demonstrating the migration potential of control, SEPT9-Knockdown and SEPT9- Overexpression cells (×100) (*p < 0.05, significant difference versus control; △p < 0.05, significant difference versus knockdown)

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