Fig. 3: Overexpression of SEPT9_i1 promotes lung metastases after tail vein injection.

a 1 × 106 cells per group were injected into the mammary fat pads of nude mice. Shown are representative tumors that formed 6 weeks post-injection. b Representative H&E-stained sections of lungs and livers of mice with control, knockdown and overexpression group tumors 6 weeks post-orthotopic injection. c Representative H&E-stained sections of lungs and livers of mice with control, knockdown and overexpression group tumors 3 weeks after tail vein injection