Fig. 4: Bioinformatic analysis of DEGs between SEPT9-KD1 and SEPT9-Ov1 cell lines. | Cell Death & Disease

Fig. 4: Bioinformatic analysis of DEGs between SEPT9-KD1 and SEPT9-Ov1 cell lines.

From: SEPT9_i1 regulates human breast cancer cell motility through cytoskeletal and RhoA/FAK signaling pathway regulation

Fig. 4

a Volcano plots for all the genes comparing SEPT9-KD1 and SEPT9- Ov1. The red and green dots indicated up- and down-regulated DEGs with FDR < 0.05, while black dots indicated those without statistical significance. b KEGG pathway terms enriched by DEGs between SEPT9-KD1 and SEPT9- Ov1 cell lines, here we listed reference canonical pathways (all p < 0.05) belonging to “Cellular Process” and “Environmental Information Processing”. c Heatmap plot of some related differentially expressed genes across all samples. Columns represent genes and rows represent samples. d β-actin, CDC42 and SRC mRNA expression were analyzed by real-time RT-PCR (***p < 0.001, *p < 0.05)

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