Fig. 5: Septin-9 filaments colocalize with F-actin and microtubules, regulate the expression of β-actin and β-tubulin. | Cell Death & Disease

Fig. 5: Septin-9 filaments colocalize with F-actin and microtubules, regulate the expression of β-actin and β-tubulin.

From: SEPT9_i1 regulates human breast cancer cell motility through cytoskeletal and RhoA/FAK signaling pathway regulation

Fig. 5

a Confocal images of septin-9 (green) and actin stress fibers (phalloidin; red) in control, knockdown and overexpression group cells. 3D reconstruction reveals that septin-9 filaments colocalize with F-actin stress fibers. b Confocal images of septin-9 (green) and microtubules (red) in control, knockdown and overexpression group cells. It reveals that septin-9 filaments colocalize with microtubules. c, d β-actin and β-tubulin protein expression were analyzed by western blot (*p < 0.05). e Cdc42, Rac and RhoA protein expression were analyzed by western blot

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