Fig. 6: ROS production in NRK-52E cells induced by H24R4 or/and LPS was regulated by Cx43 channels. | Cell Death & Disease

Fig. 6: ROS production in NRK-52E cells induced by H24R4 or/and LPS was regulated by Cx43 channels.

From: Inhibition of gap junction composed of Cx43 prevents against acute kidney injury following liver transplantation

Fig. 6

a–c Effects of heptanol (2 mM, 1 h), Gap26 (300 μM, 1 h), and RA (10 μM, 24 h) on ROS production at low- and high-density cell culture exposed to H24R4, LPS (5 μg/ml, 24 h), or a combination of H24R4 and LPS. n = 6, *P < 0.05 vs control; #P < 0.05 vs the same treatment groups at low-density cell culture. d Specific siRNA decreased the content of ROS when exposed to H24R4, LPS (5 μg/ml, 24 h), or a combination of H24R4 and LPS. n = 5, *P < 0.05 vs control; #P < 0.05 vs the H24R4 group; △P < 0.05 vs the LPS group; ▲P < 0.05 vs H24R4 + LPS group

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