Table 1 Genotypic analysis of embryos from Tie2-Cre+Hsp60f/+ × Hsp60f/f intercrosses

From: Heat shock protein 60 regulates yolk sac erythropoiesis in mice

Genotype age

Tie2-Cre Hsp60f/+

Tie2-Cre Hsp60f/f

Tie2-Cre+ Hsp60f/+

Tie2-Cre+ Hsp60f/f

Total

E8.5

49 (25.9)

48 (25.4)

51 (27.0)

41 (21.7)

189

E9.5

26 (18.4)

35 (24.8)

43 (30.5)

37 (26.2)a

141

E10.5

13 (21.0)

19 (30.6)

15 (24.2)

15 (24.2)b

62

E11.5

14 (35.9)

7 (17.9)

10 (25.6)

8 (20.5)c

39

E12.5

3 (30.0)

3 (30.0)

3 (30.0)

1 (10.0)c

10

E13.5

7 (24.1)

12 (41.4)

6 (20.7)

4 (13.8)c

29

P10

36 (39.6)

26 (28.6)

29 (31.9)

0 (0.0)

91

Expected (%)

25.0

25.0

25.0

25.0

100

  1. aAll embryos are pale
  2. bAll embryos are pale and growth retarded
  3. cAll embryos are dead and almost absorbed