Fig. 6: miR-3163 enhances the antitumor effect of sorafenib on the intrahepatic growth of MHCC97-H cells in the liver of nude mice. | Cell Death & Disease

Fig. 6: miR-3163 enhances the antitumor effect of sorafenib on the intrahepatic growth of MHCC97-H cells in the liver of nude mice.

From: MicroRNA-3163 targets ADAM-17 and enhances the sensitivity of hepatocellular carcinoma cells to molecular targeted agents

Fig. 6

MHCC97-H cells transfected with vectors (control miRNA or miR-3163) were injected into the liver of nude mice through hepatic portal vein injection. The mice received oral administration of indicated concentrations of sorafenib. After treatment, the mice underwent microPET screening and were harvested to collect tumor tissues. The results are shown as images of micro-PET or quantitative analysis (a), images of livers with lesions (b), represented images of livers with lesions from each group (c), relative radio-activation of livers (d), or the relative area of lesions (e). *P < 0.05

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