Fig. 4: miR-223 influences doxorubicin resistance of HCC cells via regulation of autophagy.

a Relative cell viability (mean ± SD) for chloroquine-treated and miR-223 or NC inhibitor transfected HepG2, HuH-7, SNU-387, and SNU-449 cells treated with doxorubicin for 48 h. b IC50 values of doxorubicin in chloroquine-treated and miR-223 or NC inhibitor transfected HCC cells (n.s. p > 0.05, miR-223 inhibitor plus chloroquine vs. NC inhibitor plus chloroquine)