Fig. 1: RPPH1 is associated with poor prognosis in CRC patients. | Cell Death & Disease

Fig. 1: RPPH1 is associated with poor prognosis in CRC patients.

From: LncRNA RPPH1 promotes colorectal cancer metastasis by interacting with TUBB3 and by promoting exosomes-mediated macrophage M2 polarization

Fig. 1

a The schematic of screening target lncRNAs. b Heatmap of the screening lncRNAs with a fold change > 2 or <0.5 and p < 0.05 from seven CRC tissues and paired normal adjacent tissues (NATs). c Heatmap of 31 lncRNAs with a fold change > 4 and transcript abundance >100. d RPPH1 RNA levels were quantified in 61 paired of CRC tissues and NATs using qRT-PCR. e Fold change of RPPH1 expression levels in 61 paired CRC tissues. f The relationship between RPPH1 expression levels and TNM stage. g Representative images of the ISH of RPPH1 expression (brown) in the paraffin-embedded CRC tissues of different TNM stages. Scale bar = 100 μm. h, i Kaplan–Meier curves for OS (h) and DFS (i) of CRC patients with low vs. high expression of RPPH1. Values are represented as mean ± SD

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