Fig. 2: RAI16−/− mice have more severe DSS induced colitis.
From: Retinoid acid induced 16 deficiency aggravates colitis and colitis-associated tumorigenesis in mice
a Body weight of WT and RAI16−/− mice was determined daily. b Colitis severity was determined by disease activity index (including bleeding and diarrhea, etc.)on day 7. c The representatives of excised colons. d The lengths of excised colons. e The weights of excised colons. f Mucosal histology of the distal colon was examined on day 9 via H&E staining. g Histological scores were determined. Densitometric analysis for six independent experiments. Data shown are mean ± SD. *p < 0.05, **p < 0.01, ***p < 0.001.
