Fig. 4: OPCs transplantation enhanced the expression of β-catenin in endothelial cells. | Cell Death & Disease

Fig. 4: OPCs transplantation enhanced the expression of β-catenin in endothelial cells.

From: Oligodendrocyte precursor cells transplantation protects blood–brain barrier in a mouse model of brain ischemia via Wnt/β-catenin signaling

Fig. 4

a β-catenin (green) was mainly expressed on the cerebrovasculature (red). Astrocytes (GFAP+) and neuron (NeuN+) expressed little β-catenin. Scale bar = 25 µm. b Images of β-catenin (green) and endothelial marker CD31 (red) in the peri-infarct area after 3 days following MCAO in Sham, Stroke + PBS, and Stroke + OPC groups. Bar graph showed OPCs upregulated the expression of β-catenin. Data are mean ± SD, n = 6–8 per group, ***p < 0.001, as compared with Stroke + PBS group. Scale bar = 50 µm. S + P: Stroke + PBS; S + O: Stroke + OPC.

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