Fig. 1: miR-26a/b are decreased in OLP patients.
From: MicroRNA-26a/b have protective roles in oral lichen planus
a miR-26a/b levels in human oral epithelial samples determined by real-time PCR. b Correlation of fold change between TNFα and miR-26a/b in oral epitheliums from OLP patients (r = −0.8118, P = 3.59 × 10−6, Spearman’s correlation test for miR-26a; r = -0.8383, P = 2.36 × 10-6, Spearman’s correlation test for miR-26b). c miR-26a/b levels in serum of participants measured by real-time PCR. d Correlation between TNFα concentrations and miR-26a/b levels in serum of OLP patients (r = −0.6488, P = 5.18 × 10-8, Spearman’s correlation test for miR-26a; r = −0.7227, P = 5.19 × 10-8, Spearman’s correlation test for miR-26b). e qPCR analysis of OLP saliva showing 40% decreases of miR-26a/b versus healthy controls. f Correlation between TNFα status and miR-26a/b expression in saliva derived from OLP patients (r = −0.6128, P = 1.57 × 10−7, Spearman’s correlation test for miR-26a; r = −0.7525, P = 1.63 × 10−7, Spearman’s correlation test for miR-26b). **P < 0.01, ***P < 0.001 vs. corresponding healthy controls; n = 14 each group.
