Fig. 3: Flow cytometric analysis and in vivo tumorigenesis assay. | Cell Death & Disease

Fig. 3: Flow cytometric analysis and in vivo tumorigenesis assay.

From: Circular RNA circCTNNA1 promotes colorectal cancer progression by sponging miR-149-5p and regulating FOXM1 expression

Fig. 3

a, b Flow cytometry analysis was carried out to determine the changes in the cell cycle profile following circCTNNA1 knockdown or overexpression in SW620 and SW480 cells. c SW620 cells stably transfected with overexpression or SW480 transfected with shRNA vector were subcutaneously injected into female nude mice. d, e The tumor weight and volume were significantly increased in the circCTNNA1 overexpression group, and decreased in the sh-circCTNNA1 group. f IHC staining were conducted and IHC scores were calculated to determine the effects of circCTNNA1 on the expression of FOXM1 and downstream related proteins in xenograft tumor tissues. ***p < 0.001.

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