Fig. 1: PIN1 is upregulated in gastric cancer and indicates poorer prognosis.
From: Deficiency of microRNA-628-5p promotes the progression of gastric cancer by upregulating PIN1
a, b The mRNA and protein level of PIN1 in different gastric cancer cell lines and human GES. The relative protein densitometry was analyzed. c, d The PIN1 mRNA expression in the cancer and corresponding adjacent tissue (n = 24, *p < 0.05, **p < 0.01, ***p < 0.001, ns, no significance). e Representative protein expression of PIN1 from tissues above. f Representative immunohistochemical staining of PIN1 in the cancer and adjacent tissue. g The PIN1 expression in cancer and adjacent tissue (n = 66, *p < 0.05). h, i The correlation of PIN1 expression with TNM stage/lymphatic metastasis in gastric cancer (n = 66, *p < 0.05). j The ROC curves based on PIN1 expression to predict patients’ survival time. k The PIN1 expression based overall survival of gastric cancer patient by Kaplan–Meier analyses (n = 66, p < 0.01). l Representative immunohistochemical staining of PIN1 in the primary and metastasis cancer tissues. m The PIN1 expression in primary and metastasis cancer tissues (n = 27, *p < 0.05). Scale bars: 200 μm.
