Fig. 2: PIN1 facilitates the progression of gastric cancer.
From: Deficiency of microRNA-628-5p promotes the progression of gastric cancer by upregulating PIN1
a Detect the proliferation of AGS that exogenous expressed PIN1 or negative control by CCK-8. b The cell cycle of cells in a are detected by flow cytometry. c, d The colony formation of cells in a and the clone number was counted. e Detect the proliferation of MGC-803 that interfered PIN1 or not by CCK-8. f The cell cycle of cells in e are detected by flow cytometry. g, h The colony formation of cells in e and the clone number was counted. i, j Transwell test to detect the migration and invasion of treated AGS. The migrated and invaded cells were counted. k, l Transwell test to detect the migration and invasion of treated MGC-803. The migrated and invaded cells were counted. m The protein expression of PIN1 downstreams after intervened PIN1 in AGS and MGC-803. The data are shown as the mean ± s.d. (n = 3) in cell lines. *p < 0.05, **p < 0.01, ***p < 0.001. Scale bars: 200 μm.
