Fig. 6: PIN1 reverses the miR-628-5p-mediated suppression of gastric cancer.
From: Deficiency of microRNA-628-5p promotes the progression of gastric cancer by upregulating PIN1
a The protein expression of PIN1 in MGC-803 that cotransfected miR-628-5p mimic and PIN1 overexpression plasmid. The relative protein densitometry was analyzed. b CCK-8 to detect the proliferation of cells in a. c, d The colony formation of cells in a and the clone number was counted. e, f Transwell test to detect the migration and invasion of cells in a. The migrated and invaded cells were counted. g The protein expression of PIN1 in AGS that cotransfected miR-628-5p inhibitor and PIN1 shRNA plasmid. The relative protein densitometry was analyzed. h CCK-8 to detect the proliferation of cells in g. i, j The colony formation of cells in g and the clone number was counted. k, l Transwell test to detect the migration and invasion of cells in g. The migrated and invaded cells were counted. The data are shown as the mean ± s.d. (n = 3) in cell lines. *p < 0.05, **p < 0.01, ***p < 0.001. Scale bars: 200 μm.
