Table 1 Summary of GSH associated miRNAs in cancer.

From: Crosstalk between noncoding RNAs and ferroptosis: new dawn for overcoming cancer progression

Name

Associated cancer type

Target

Influence to GSH

Model of evidence

Reference

miR-27a

Bladder cancer, colorectal cancer

SLC7A11, ZBTB10

Up/Down

Cell culture, animal models

42,43

miR-143

Colorectal cancer

GPX

Up

Animal models

199

miR-17

Prostate cancer

GPX2

Up

Cell culture, animal models

56

miR-17-3p

Prostate cancer

GPX2

Up

Cell culture, animal models

57

miR-196a

Lung cancer

GPX3

Up

Cell culture, animal models

58

miR-921

Lung cancer

GPX3

Up

Cell culture

59

miR-124

Colorectal cancer

GST

Up

Cell culture, animal models

48

Let-7a-5p

Prostate cancer

GST

Up

Cell culture, animal models

49

miR-92b-3p

Prostate cancer

GST

Up

Cell culture, animal models

49

miR-129-5P

Colorectal cancer cells

GST

Up

Cell culture

50

miR-144

Prostate cancer

GST

Up

Cell culture, animal models

51

miR-153-1/2

Prostate cancer

GST

Up

Cell culture, animal models

51

miR-302c-5p

Colorectal cancer

GST

Up

Cell culture

50

miR-3664-5p

Colorectal cancer

GST

Up

Cell culture

50

miR-3714

Colorectal cancer

GST

Up

Cell culture

50

miR-513a-3p

Colorectal cancer, lung cancer

GST

Up

Cell culture

200

miR-590-3p/5p

Prostate cancer

GST

Up

Cell culture, animal models

51

miR-133a/b

Bladder cancer, lung cancer, prostate cancer, colorectal cancer, ovarian cancer, head and neck squamous cell carcinoma

GST

Up

Cell culture, animal models

52,53,201

miR-130b

Ovarian cancer

GST

Up

Cell culture

202

miR-186

Ovarian cancer

GST

Up

Cell culture

203

miR-34b

Prostate cancer

MYC

Up

Cell culture

204

miR-K12-11

Kaposi’s sarcoma

xCT

Up

Cell culture

205

miR-18a

Hepatocellular carcinoma

GCL

Down

Cell culture, animal models

37

miR-218

Bladder cancer

GCL

Down

Cell culture

38

miR-21

Lung cancer

GSH

Down

Cell culture

44

miR-24-2

Colorectal cancer

GSH

Down

Clinical samples

45

miR-497

Cervical cancer

GSH

Down

Cell culture

46

miR-503

Hepatocellular carcinoma

GSH

Down

Cell culture

47

miR-152

Hepatocellular carcinoma

GST

Down

Cell culture

39

miR-155

Lung cancer

GST

Down

Cell culture

40

miR-326

Glioma

PKM2

Down

Cell culture

41

miR-125b

Chronic lymphocytic leukemias

GSH

Unknown

Cell culture

206