Table 2 Summary of iron associated miRNAs in cancer.

From: Crosstalk between noncoding RNAs and ferroptosis: new dawn for overcoming cancer progression

Name	Associated cancer type	Target	Influence to iron	Model of evidence	Reference
miR-150	Hepatocellular carcinoma	FPN	Up	Cell culture	⁷⁶
miR-17-5p	Multiple myeloma	FPN	Up	Cell culture, animal models	⁶⁶
miR-20a	Lung cancer	FPN	Up	Cell culture	⁶⁷
miR-492	Prostate cancer	FPN	Up	Cell culture, animal models	⁶⁸
miR-194	Colorectal cancer	TFR1, FPN1	Up	Clinical samples	⁶³
miR-449a	Glioma	CDGSH iron sulfur domain 2	Down	Cell culture, animal models	²⁰⁷
miR-149	Colorectal cancer	DMT1	Down	Clinical samples	⁶³
miR-19a	Colorectal cancer	DMT1	Down	Clinical samples	⁶³
miR-181a-5p	Prostate cancer	FHC	Down	Cell culture, animal models	⁷⁰
miR-19b-1-5p	Prostate cancer	FHC	Down	Cell culture, animal models	⁷⁰
miR-19b-3p	Prostate cancer	FHC	Down	Cell culture, animal models	⁷⁰
miR-210-3p	Prostate cancer	FHC	Down	Cell culture, animal models	⁷⁰
miR-362-5p	Prostate cancer	FHC	Down	Cell culture, animal models	⁷⁰
miR-616-3p	Prostate cancer	FHC	Down	Cell culture, animal models	⁷⁰
miR-638	Prostate cancer	FHC	Down	Cell culture, animal models	⁷⁰
miR-200b	Hepatocellular carcinoma, breast cancer	Ferritin	Down	Cell culture	^65,71
miR-133a	Colorectal cancer, breast cancer	FLC	Down	Cell culture	^63,72
miR-29	Lung cancer	Iron-responsive element binding protein 2	Down	Clinical samples	²⁰⁸
miR-210	Renal cancer, head and neck paragangliomas, breast cancer, colorectal cancer, and oropharyngeal squamous cell carcinomas	ISCU, TFR1	Down	Cell culture, animal models	^{73,74,209,210,211}
miR-126	Malignant mesothelioma	Mitochondria-destabilizing stress signals	Down	Cell culture, animal models	²¹²
miR-7-5p	Ovarian cancer, colorectal cancer	Mitoferrin	Down	Cell culture	³⁰
miR-122	Hepatocellular cancer	Nocturnin	Down	Cell culture, animal models	²¹³
miR-34a	Lung cancer	P53	Down	Cell culture, animal models	²¹⁴
miR-141	Colorectal cancer	TFR1	Down	Clinical samples	⁶³
miR-145	Colorectal cancer	TFR1	Down	Clinical samples	⁶³
miR-152	Hepatocellular carcinoma	TFR1	Down	Cell culture, animal models	⁶⁴
miR-182	Colorectal cancer	TFR1	Down	Clinical samples	⁶³
miR-200a	Hepatocellular carcinoma	TFR1	Down	Cell culture	⁶⁵
miR-22	Hepatocellular cancer	TFR1	Down	Cell culture	⁶⁵
miR-31	Colorectal cancer	TFR1	Down	Clinical samples	⁶³
miR-320	Hepatocellular cancer	TFR1	Down	Cell culture	⁶⁵
miR-758	Colorectal cancer	TFR1	Down	Clinical samples	⁶³
miR-107	Hepatocellular carcinoma	–	Inhibited by iron	Cell culture, animal models	⁷⁵
miR-125b	Ovarian cancer	–	Inhibited by iron	Cell culture	⁷⁶
miR-30d	Hepatocellular carcinoma	–	Inhibited by iron	Cell culture, animal models	⁷⁵
miR-146a	Ovarian cancer	–	Induced by iron	Cell culture	⁷⁶
miR-150	Ovarian cancer	–	Induced by iron	Cell culture	⁷⁶
miR-214-3p	Neuroblastoma	–	Induced by iron	Cell culture	⁷⁷
miR-584	Neuroblastoma	–	Induced by iron	Cell culture	⁷⁷

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Table 2 Summary of iron associated miRNAs in cancer.

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