Fig. 1: Microarray screening of ESCC-associated miRNAs.
From: The miR-1224-5p/TNS4/EGFR axis inhibits tumour progression in oesophageal squamous cell carcinoma
a Heatmap showing the differentially expressed miRNAs in six ESCC tissues and adjacent non-malignant tissues. b The normalised intensities of hsa-let-7c, hsa-miR-1224-5p, hsa-miR-320c and hsa-miR-939 in the microarray assay. c–f qRT-PCR was used to analyse the expression of hsa-let-7c, hsa-miR-1224-5p, hsa-miR-320c and hsa-miR-939 in ESCC tissues (n = 12). g The expression of miR-1224-5p was examined by qRT-PCR in independent ESCC samples (n = 75). h Kaplan–Meier curve showing a positive correlation between low miR-1224-5p expression and lower survival rates in ESCC samples (n = 75). i–l Transcript levels of miR-1224-5p in normal tissues and ESCC tissues from GSE55856 and GSE43732, in normal tissues and HNSCC tissues from GSE34496, and in tissues from locally advanced rectal cancer patients with incomplete (NCR) and complete responses (CR) to neoadjuvant chemoradiotherapy (capecitabine + oxaliplatin + 45 Gy of pelvic conformal radiotherapy) from GSE29298; ** p < 0.01, *** p < 0.001.
