Fig. 7: METTL3 knockdown restores autophagy inhibited by propofol. | Cell Death & Disease

Fig. 7: METTL3 knockdown restores autophagy inhibited by propofol.

From: Propofol-induced MiR-20b expression initiates endogenous cellular signal changes mitigating hypoxia/re-oxygenation-induced endothelial autophagy in vitro

Fig. 7

a–f Built the H/R model after knockdown of METTL3. Western blotting analysis of the autophagy-related protein and DGCR8 levels. g–l Built the H/R model after knockdown of METTL3 and treated the cells with or without propofol at re-oxygenation for 4 h. Western blotting analysis of the autophagy-related protein and DGCR8 levels. Data are shown as the mean ± SEM (n = 3); *p < 0.05, **p < 0.01, ***p < 0.001.

Back to article page